ruffle assembly

Term ID

GO:0097178

Synonyms

• membrane ruffle formation
• membrane ruffling

Definition

The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO