DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity

Term ID

GO:0072586

Synonyms

Definition

Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.

References

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: ATPase regulator activity enzyme regulator activity

ATPase regulator activity enzyme regulator activity Show first 5 Terms
has subtype: DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity

DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations