siRNA-mediated gene silencing by inhibition of translation

Term ID

GO:0070549

Synonyms

• down regulation of translation involved in RNA interference
• down-regulation of translation involved in RNA interference
• downregulation of translation involved in RNA interference
• inhibition of translation involved in RNA interference
• negative regulation of translation involved in RNA interference
• RNA interference, negative regulation of translation

Definition

An siRNA-mediated post-transcriptional gene silencing pathway that blocks the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically mediate repression of translation if the siRNA perfectly complements elements located in the 3' untranslated region of target mRNAs. 18771919

References

Ontology

GO: Biological Process    QuickGO    AmiGO