R-loop processing

Term ID

GO:0062176

Synonyms

• R-loop disassembly

Definition

A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability. (3)

References

Ontology

GO: Biological Process    QuickGO    AmiGO