class II DNA-(apurinic or apyrimidinic site) endonuclease activity

Term ID

GO:0052720

Synonyms

• abasic deoxyendoribonuclease activity
• AP deoxyendoribonuclease activity
• apurinic deoxyendoribonuclease activity
• apyrimidinic deoxyendoribonuclease activity
• class II DNA-(apurinic or apyrimidinic site) lyase activity

Definition

Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. 19401441

References

Ontology

GO: Molecular Function    QuickGO    AmiGO