6-methylsalicylic acid synthase activity

Term ID

GO:0050641

Synonyms

• 6-MSAS activity
• acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)
• MSAS activity

Definition

Catalysis of the reaction: acetyl-CoA + 3 H+ + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO2 + 4 CoA + H2O + NADP+. 2.3.1.165

References

• EC:2.3.1.165
• KEGG_REACTION:R07253
• MetaCyc:2.3.1.165-RXN
• RHEA:12240

Ontology

GO: Molecular Function    QuickGO    AmiGO