ATPase-coupled transmembrane transporter activity

Term ID

GO:0042626

Synonyms

• ABC transporter
• ABC-type efflux permease activity
• ABC-type efflux porter activity
• ABC-type uptake permease activity
• ATP binding cassette transporter
• ATP-binding cassette (ABC) transporter activity
• ATP-binding cassette transporter
• ATP-coupled transmembrane transporter activity
• ATP-dependent transmembrane transporter activity
• ATPase activity, coupled to movement of substances
• ATPase activity, coupled to transmembrane movement of substances
• hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
• mating pheromone exporter
• P-P-bond-hydrolysis-driven transmembrane transporter activity
• P-P-bond-hydrolysis-driven transporter

Definition

Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source. 0815340729

References

• EC:7.2.2.-
• Reactome:R-HSA-1467457
• Reactome:R-HSA-2161506
• Reactome:R-HSA-2161538
• Reactome:R-HSA-9033499
• Reactome:R-HSA-9033505
• Reactome:R-HSA-9659680
• Reactome:R-HSA-9750546
• Reactome:R-HSA-9750617
• Reactome:R-HSA-9753278
• Reactome:R-HSA-9753283
• Reactome:R-HSA-9753284
• Reactome:R-HSA-9759454
• Reactome:R-HSA-9759461
• Reactome:R-HSA-9794120
• Reactome:R-HSA-9794572

Ontology

GO: Molecular Function    QuickGO    AmiGO