granulocyte-macrophage colony-stimulating factor signaling pathway

Term ID

GO:0038157

Synonyms

• CSF2 signaling pathway
• GM-CSF receptor signaling pathway
• GM-CSF signaling pathway
• granulocyte-macrophage colony-stimulating factor receptor signaling pathway
• granulocyte-macrophage colony-stimulating factor signalling pathway

Definition

The series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors. 17027509

References

Ontology

GO: Biological Process    QuickGO    AmiGO