negative regulation of signal transduction by receptor internalization

Term ID

GO:0038011

Synonyms

• negative regulation of signaling pathway by receptor endocytosis

Definition

Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO