prostaglandin H2 endoperoxidase reductase activity

Term ID

GO:0036130

Synonyms

• PGH2 9,11-endoperoxidase
• PGH2 9-,11-endoperoxide reductase

Definition

Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate). (3)

References

• KEGG_REACTION:R02264
• RHEA:45312
• Reactome:R-HSA-2161549

Ontology

GO: Molecular Function    QuickGO    AmiGO