ubiquitin-ubiquitin ligase activity

Term ID

GO:0034450

Synonyms

• E4

Definition

Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin = Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue. (2)

References

• Reactome:R-HSA-937050
• Reactome:R-HSA-975122

Ontology

GO: Molecular Function    QuickGO    AmiGO