chondroitin B lyase activity

Term ID

GO:0033999

Synonyms

• ChnB
• chonB
• chondroitinase B activity
• dermatan sulfate lyase activity

Definition

Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate. 4.2.2.19

References

• EC:4.2.2.19
• MetaCyc:4.2.2.19-RXN

Ontology

GO: Molecular Function    QuickGO    AmiGO