peptide-methionine (R)-S-oxide reductase activity

Term ID

GO:0033743

Synonyms

• methionine S-oxide reductase (R-form oxidizing) activity
• methionine S-oxide reductase activity
• methionine sulfoxide reductase activity
• methionine sulfoxide reductase B activity
• MsrB
• peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity
• PilB
• pMRsr
• pMSR
• protein-methionine-R-oxide reductase activity
• selenoprotein R
• SelR
• SelX

Definition

Catalysis of the reaction: peptide-L-methionine + H2O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin. 1.8.4.12

References

• EC:1.8.4.12
• KEGG_REACTION:R07607
• MetaCyc:1.8.4.12-RXN
• RHEA:24164
• Reactome:R-HSA-5676917

Ontology

GO: Molecular Function    QuickGO    AmiGO