integrin activation

Term ID

GO:0033622

Synonyms

integrin complex activation
integrin complex assembly

Definition

The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands. (2)

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: protein-containing complex assembly

protein-containing complex assembly Show first 5 Terms
negatively regulated by: negative regulation of integrin activation

negative regulation of integrin activation Show first 5 Terms
positively regulated by: positive regulation of integrin activation positive regulation of integrin activation by cell surface receptor linked signal transduction

positive regulation of integrin activation positive regulation of integrin activation by cell surface receptor linked signal transduction Show first 5 Terms
regulated by: regulation of integrin activation

regulation of integrin activation Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations