purine-rich negative regulatory element binding

Term ID

GO:0032422

Synonyms

• PNR element binding

Definition

Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes. 9819411

References

Ontology

GO: Molecular Function    QuickGO    AmiGO