retromer, tubulation complex

Term ID

GO:0030905

Synonyms

• heterodimeric membrane-deforming retromer subcomplex
• retromer complex, outer shell
• SNX-BAR dimer

Definition

The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodeling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6. (2)

References

Ontology

GO: Cellular Component    QuickGO    AmiGO