Search Ontology:
GO: Cellular Component

beta-catenin destruction complex

Term ID
GO:0030877
Synonyms
  • 23S APC complex
  • APC-Axin-1-beta-catenin complex
  • Axin-APC-beta-catenin-GSK3B complex
  • BDC
  • beta-catenin degradation complex
Definition
A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome. 14600025
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
Citations
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