pyrrolysine incorporation

Term ID

GO:0030631

Synonyms

• lysine methylamine methyltransferase cofactor adduct incorporation
• monomethylamine methyltransferase cofactor lysine adduct incorporation

Definition

The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases. (2)

References

• RESID:AA0321

Ontology

GO: Biological Process    QuickGO    AmiGO