antigen processing and presentation of endogenous peptide antigen via MHC class I

Term ID

GO:0019885

Synonyms

• antigen presentation, endogenous peptide antigen
• antigen processing, endogenous antigen via major histocompatibility complex class I
• antigen processing, endogenous antigen via MHC class I
• endogenous peptide antigen processing and presentation via MHC class I

Definition

The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO