procollagen-proline 4-dioxygenase complex

Term ID

GO:0016222

Synonyms

procollagen-proline, 2-oxoglutarate-4-dioxygenase complex
prolyl 4-hydroxylase complex

Definition

A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase. (2)

References

Ontology

GO: Cellular Component QuickGO AmiGO

Relationships

is a type of: endoplasmic reticulum protein-containing complex oxidoreductase complex

endoplasmic reticulum protein-containing complex oxidoreductase complex Show first 5 Terms
has subtype: procollagen-proline 4-dioxygenase complex, alpha(I) type procollagen-proline 4-dioxygenase complex, alpha(II) type procollagen-proline 4-dioxygenase complex, alpha(III) type

procollagen-proline 4-dioxygenase complex, alpha(I) type procollagen-proline 4-dioxygenase complex, alpha(II) type procollagen-proline 4-dioxygenase complex, alpha(III) type Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations