Search Ontology:

GO: Biological Process

membrane protein ectodomain proteolysis

Term ID

GO:0006509

Synonyms

ectoderm shedding
ectodomain cleavage
membrane protein solubilization
receptor shedding

Definition

The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). http://www.copewithcytokines.de/

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: membrane protein proteolysis

membrane protein proteolysis Show first 5 Terms
has subtype: constitutive protein ectodomain proteolysis

constitutive protein ectodomain proteolysis Show first 5 Terms
inverse has_part: epidermal growth factor receptor ligand maturation

epidermal growth factor receptor ligand maturation Show first 5 Terms
negatively regulated by: negative regulation of membrane protein ectodomain proteolysis

negative regulation of membrane protein ectodomain proteolysis Show first 5 Terms
positively regulated by: positive regulation of membrane protein ectodomain proteolysis

positive regulation of membrane protein ectodomain proteolysis Show first 5 Terms
regulated by: regulation of membrane protein ectodomain proteolysis

regulation of membrane protein ectodomain proteolysis Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations