Search Ontology:
GO: Biological Process

tricarboxylic acid cycle

Term ID
GO:0006099
Synonyms
  • citric acid cycle
  • Krebs cycle
  • TCA cycle
Definition
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. 0198506732
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is part of
is a type of
has subtype
Phenotype
Phenotype caused by Genes
Citations
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