ribonuclease III activity

Term ID

GO:0004525

Synonyms

pre-mRNA 3'-end processing endonuclease
ribonuclease 3 activity
RNase III activity

Definition

Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt. (2)

References

EC:3.1.26.3
MetaCyc:3.1.26.3-RXN
Reactome:R-HSA-203862
Reactome:R-HSA-203893
Reactome:R-HSA-426464
Reactome:R-HSA-9708292
Reactome:R-HSA-9708408
Reactome:R-HSA-9820840

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: double-stranded RNA-specific ribonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters

double-stranded RNA-specific ribonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters Show first 5 Terms
has subtype: bidentate ribonuclease III activity

bidentate ribonuclease III activity Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations