dopamine beta-monooxygenase activity

Term ID

GO:0004500

Synonyms

• (3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity
• 3,4-dihydroxyphenethylamine beta-oxidase activity
• 3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating)
• 4-(2-aminoethyl)pyrocatechol beta-oxidase activity
• dopa beta-hydroxylase activity
• dopamine b-hydroxylase activity
• dopamine beta-hydroxylase activity
• dopamine beta-oxidase activity
• dopamine hydroxylase activity
• dopamine-B-hydroxylase activity
• MDBH (membrane-associated dopamine beta-monooxygenase)
• oxygenase, dopamine beta-mono-
• phenylamine beta-hydroxylase activity
• SDBH (soluble dopamine beta-monooxygenase)

Definition

Catalysis of the reaction: L-ascorbate + dopamine + O2 = (R)-noradrenaline + dehydroascorbate + H2O. 1.14.17.1

References

• EC:1.14.17.1
• KEGG_REACTION:R02535
• MetaCyc:DOPAMINE-BETA-MONOOXYGENASE-RXN
• RHEA:19117
• Reactome:R-HSA-209891

Ontology

GO: Molecular Function    QuickGO    AmiGO