histone deacetylase activity

Term ID

GO:0004407

Synonyms

Definition

Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes. 9893272

References

EC:3.5.1.98
MetaCyc:3.5.1.98-RXN
RHEA:58196
Reactome:R-HSA-2545203
Reactome:R-HSA-2545253
Reactome:R-HSA-3769447
Reactome:R-HSA-3777129
Reactome:R-HSA-3782637
Reactome:R-HSA-3782655
Reactome:R-HSA-427514
Reactome:R-HSA-433672
Reactome:R-HSA-6805650

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: histone modifying activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides protein lysine deacetylase activity

histone modifying activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides protein lysine deacetylase activity Show first 5 Terms
has subtype: histone H3K deacetylase activity histone H4K deacetylase activity NAD-dependent histone deacetylase activity NAD-independent histone deacetylase activity

histone H3K deacetylase activity histone H4K deacetylase activity NAD-dependent histone deacetylase activity NAD-independent histone deacetylase activity Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations