heme oxygenase (decyclizing) activity

Term ID

GO:0004392

Synonyms

haem oxidase activity
haem oxygenase (decyclizing) activity
haem oxygenase activity
heme oxidase activity
heme oxygenase activity
heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
ORP33 proteins

Definition

Catalysis of the reaction: heme b + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = biliverdin + CO + Fe2+ + H+ + 3 H2O + 3 oxidized [NADPH-hemoprotein reductase].

References

EC:1.14.14.18
MetaCyc:HEME-OXYGENASE-DECYCLIZING-RXN
RHEA:21764
Reactome:R-HSA-189398

Ontology

GO: Molecular Function QuickGO AmiGO

Relationships

is a type of: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Show first 5 Terms
negatively regulated by: negative regulation of heme oxygenase activity

negative regulation of heme oxygenase activity Show first 5 Terms
positively regulated by: positive regulation of heme oxygenase activity

positive regulation of heme oxygenase activity Show first 5 Terms
regulated by: regulation of heme oxygenase activity

regulation of heme oxygenase activity Show first 5 Terms

Phenotype

Phenotype caused by Genes

Citations