glutamate synthase (NADPH) activity

Term ID

GO:0004355

Synonyms

• glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity
• glutamate synthetase (NADP) activity
• glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity
• glutamine-ketoglutaric aminotransferase activity
• GOGAT activity
• L-glutamate synthase activity
• L-glutamate synthetase activity
• L-glutamate:NADP+ oxidoreductase (transaminating)
• L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity
• NADPH GOGAT
• NADPH-dependent glutamate synthase activity
• NADPH-glutamate synthase activity
• NADPH-linked glutamate synthase

Definition

Catalysis of the reaction: 2 L-glutamate + NADP+ = 2-oxoglutarate + L-glutamine + H+ + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+. 1.4.1.13

References

• EC:1.4.1.13
• KEGG_REACTION:R00114
• MetaCyc:GLUGLNSYN-PWY
• MetaCyc:GLUTAMATESYN-RXN
• MetaCyc:GLUTSYN-PWY
• RHEA:15501

Ontology

GO: Molecular Function    QuickGO    AmiGO