fatty acid synthase activity

Term ID

GO:0004312

Synonyms

• acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)
• fatty-acid synthase activity

Definition

Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+. 2.3.1.85

References

• EC:2.3.1.85
• MetaCyc:FATTY-ACID-SYNTHASE-RXN
• RHEA:14993
• Reactome:R-HSA-75872

Ontology

GO: Molecular Function    QuickGO    AmiGO