diphthine synthase activity

Term ID

GO:0004164

Synonyms

• diphthine methyltransferase activity
• S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase activity
• S-adenosyl-L-methionine:elongation factor 2 methyltransferase activity

Definition

Catalysis of the reaction: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine = diphthine-[translation elongation factor 2] + 3 H+ + 3 S-adenosyl-L-homocysteine. (3)

References

• EC:2.1.1.98
• MetaCyc:RXN-14326
• RHEA:36415
• Reactome:R-HSA-5358484

Ontology

GO: Molecular Function    QuickGO    AmiGO