DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

Term ID

GO:0003918

Synonyms

• deoxyribonucleate topoisomerase
• deoxyribonucleic topoisomerase activity
• DNA gyrase activity
• DNA topoisomerase (ATP-hydrolysing)
• DNA topoisomerase II
• DNA topoisomerase II activity
• DNA topoisomerase IV activity
• DNA topoisomerase type II activity
• DNA-gyrase activity
• topoisomerase
• topoisomerase II
• type II DNA topoisomerase activity

Definition

Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2. 8811192

References

• EC:5.6.2.2
• MetaCyc:5.99.1.3-RXN
• Wikipedia:Type_II_topoisomerase

Ontology

GO: Molecular Function    QuickGO    AmiGO