Lambert-Eaton myasthenic syndrome

Term ID

DOID:0050214

Synonyms

• Eaton-Lambert syndrome
• Lambert-Eaton syndrome
• LEMS

Definition

A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. http://en.wikipedia.org/wiki/Lambert%E2%80%93Eaton_myasthenic_syndrome

References

• ICD10CM:G70.80
• ICD9CM:358.3
• MESH:D015624
• NCI:C3155
• SNOMEDCT_US_2023_03_01:230688006
• UMLS_CUI:C0022972

Ontology

Human Disease   ( DOID:0050214 )