basophil mast progenitor cell

Term ID

CL:0002028

Synonyms

BMCP

Definition

A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa

References

Ontology

Cell Ontology

Relationships

develops from: granulocyte monocyte progenitor cell

granulocyte monocyte progenitor cell Show first 5 Terms
develops into: basophil progenitor cell mast cell progenitor

basophil progenitor cell mast cell progenitor Show first 5 Terms
is a type of: granulocytopoietic cell myeloid cell myeloid lineage restricted progenitor cell

granulocytopoietic cell myeloid cell myeloid lineage restricted progenitor cell Show first 5 Terms
has subtype: Kit-positive, integrin beta7-high basophil mast progenitor cell

Kit-positive, integrin beta7-high basophil mast progenitor cell Show first 5 Terms
capable_of: basophil differentiation mast cell differentiation

basophil differentiation mast cell differentiation Show first 5 Terms
has_part: CCAAT/enhancer-binding protein alpha endothelial transcription factor GATA-2 erythroid transcription factor

CCAAT/enhancer-binding protein alpha endothelial transcription factor GATA-2 erythroid transcription factor Show first 5 Terms
has_plasma_membrane_part: interleukin-5 receptor subunit alpha mast/stem cell growth factor receptor

interleukin-5 receptor subunit alpha mast/stem cell growth factor receptor Show first 5 Terms
lacks_plasma_membrane_part: high affinity immunoglobulin epsilon receptor subunit alpha transmembrane emp24 domain-containing protein 1

high affinity immunoglobulin epsilon receptor subunit alpha transmembrane emp24 domain-containing protein 1 Show first 5 Terms