immature B cell

Term ID

CL:0000816

Synonyms

immature B lymphocyte
immature B-cell
immature B-lymphocyte
newly formed B cell

Definition

An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation. (3)

References

Ontology

Cell Ontology

Relationships

develops from: small pre-B-II cell

small pre-B-II cell Show first 5 Terms
develops into: transitional stage B cell

transitional stage B cell Show first 5 Terms
is a type of: B cell

B cell Show first 5 Terms
has subtype: CD38-negative immature B cell Fraction E immature B cell

CD38-negative immature B cell Fraction E immature B cell Show first 5 Terms
has_not_completed: isotype switching

isotype switching Show first 5 Terms
has_plasma_membrane_part: IgM immunoglobulin complex membrane-spanning 4-domains subfamily A member 1

IgM immunoglobulin complex membrane-spanning 4-domains subfamily A member 1 Show first 5 Terms
inverse disjoint_from: mature B cell

mature B cell Show first 5 Terms
lacks_plasma_membrane_part: IgD immunoglobulin complex

IgD immunoglobulin complex Show first 5 Terms