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Cell Ontology

T-helper 2 cell

Term ID

CL:0000546

Synonyms

helper T cell type 2
T helper cells type 2
T(H)-2 cell
Th2 cell
Th2 T cell
Th2 T lymphocyte
Th2 T-cell
Th2 T-lymphocyte

Definition

A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4. (3)

References

BTO:0001679
FMA:84385

Ontology

Cell Ontology

Relationships

develops from: activated CD4-positive, alpha-beta T cell

activated CD4-positive, alpha-beta T cell Show first 5 Terms
is a type of: CD4-positive helper T cell CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell

CD4-positive helper T cell CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell Show first 5 Terms
capable_of: interleukin-4 production

interleukin-4 production Show first 5 Terms
has_part: trans-acting T-cell-specific transcription factor GATA-3

trans-acting T-cell-specific transcription factor GATA-3 Show first 5 Terms
lacks_plasma_membrane_part: C-C chemokine receptor type 6 C-X-C chemokine receptor type 3

C-C chemokine receptor type 6 C-X-C chemokine receptor type 3 Show first 5 Terms