Search Ontology:
ChEBI
tramadol
- Term ID
- CHEBI:9648
- Synonyms
-
- (+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
- CG-315E
- E-265
- rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
- tramadol
- tramadolum
- U-26225A
- Definition
- A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Grünenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia.
- References
-
- cas:27203-92-5
- drugbank:DB00193
- hmdb:HMDB0014339
- kegg.compound:C07153
- kegg.drug:D08623
- patent:GB997399
- patent:US3652589
- pubmed:22674657
- pubmed:22943675
- pubmed:22964800
- pubmed:23031839
- pubmed:23061925
- pubmed:23095734
- pubmed:23098678
- pubmed:23099620
- pubmed:23102445
- pubmed:23145962
- pubmed:23292128
- pubmed:23328338
- pubmed:23433451
- pubmed:23543914
- pubmed:23668411
- pubmed:23755929
- pubmed:23756535
- pubmed:23773348
- pubmed:23822079
- pubmed:23825758
- pubmed:23840975
- pubmed:23843224
- pubmed:23872384
- pubmed:23907474
- pubmed:23962470
- pubmed:24014188
- pubmed:25219922
- reaxys:2943832
- wikipedia.en:Tramadol
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
Phenotype
Phenotype resulting from tramadol
Phenotype where environments contain tramadol
Phenotype modified by environments containing tramadol
Phenotype affecting tramadol
Human Disease Model