Search Ontology:
ChEBI

alvocidib hydrochloride

Term ID
CHEBI:90998
Synonyms
  • (3S,4R)-4-[2-(2-chlorophenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-3-hydroxy-1-methylpiperidinium chloride
  • 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one hydrochloride
  • alvocidib HCl
  • HL 275
  • HL-275
  • HMR 1275
  • HMR-1275
  • L 86 8275
  • L86-8275
Definition
A hydrochloride salt resulting from the formal reaction of equimolar amounts of alvocidib and hydrogen chloride. A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from alvocidib hydrochloride
Phenotype where environments contain alvocidib hydrochloride
Phenotype modified by environments containing alvocidib hydrochloride
Human Disease / Model Data
Citations
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