Search Ontology:
ChEBI

ixazomib

Term ID
CHEBI:90942
Synonyms
  • ixazomib
  • MLN 2238
  • MLN-2238
  • MLN2238
  • N-[(1R)-1-borono-3-methylbutyl]-N(2)-(2,5-dichlorobenzoyl)glycinamide
Definition
A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixazomib citrate, it is used in combination therapy for treatment of multiple myeloma.
References
  • cas:1072833-77-2
  • drugcentral:5067
  • kegg.drug:D10130
  • lincs.smallmolecule:LSM-4944
  • pubmed:23514361
  • pubmed:24239172
  • pubmed:24292417
  • pubmed:24467634
  • pubmed:24904120
  • pubmed:24920586
  • pubmed:25124778
  • pubmed:25302026
  • pubmed:25325301
  • pubmed:25377318
  • pubmed:25456369
  • pubmed:25777468
  • pubmed:25832873
  • pubmed:25919767
  • pubmed:26141494
  • pubmed:26275080
  • pubmed:26337806
  • pubmed:26588946
  • pubmed:26634271
  • pubmed:26667773
  • pubmed:26709701
  • reaxys:18302358
  • wikipedia.en:Ixazomib
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from ixazomib
Phenotype where environments contain ixazomib
Phenotype modified by environments containing ixazomib
Phenotype affecting ixazomib
Human Disease Model