torkinib

Term ID

CHEBI:90679

Synonyms

2-(4-Amino-1-isopropyl-1H-pyrazolo(3,4-d)pyrimidin-3-yl)-1H-indol-5-ol
2-[4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol
PP 242
PP-242
PP242

Definition

A member of the class of pyrazolopyrimidines that is 1H-pyrazolo[3,4-d]pyrimidine substituted by isopropyl, 5-hydroxyindol-2-yl and amino groups at positions 1, 3 and 4 respectively. It is a potent inhibitor of mTOR and exhibits anti-cancer properties.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic amine biaryl hydroxyindoles phenols primary amino compound ... Show All 6 Terms

aromatic amine biaryl hydroxyindoles phenols primary amino compound pyrazolopyrimidine Show first 5 Terms
has_role: antineoplastic agent mTOR inhibitor

antineoplastic agent mTOR inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from torkinib

Phenotype where environments contain torkinib

Phenotype modified by environments containing torkinib

Human Disease / Model Data

Citations