2-(6-methoxy-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-[4-(piperazin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

Term ID

CHEBI:90627

Synonyms

2-(6-methoxy-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-[4-(piperazin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

Definition

An aromatic amide obtained by formal condensation of the amino group of 2-(6-methoxy-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-1,3-thiazole-4-carboxylic acid with the primary amino group of 4-(piperazin-1-yl)pyridin-3-amine.

References

PDBeChem:1AM
PMID:23535330
Reaxys:18325535

Ontology

ChEBI ( EBI )

Relationships

is a type of: 1,3-thiazoles aminopyridine aromatic amide aromatic ether gamma-lactam ... Show All 7 Terms

1,3-thiazoles aminopyridine aromatic amide aromatic ether gamma-lactam isoindoles N-arylpiperazine Show first 5 Terms
has_role: antineoplastic agent EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor EC 2.7.11.22 (cyclin-dependent kinase) inhibitor

antineoplastic agent EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor EC 2.7.11.22 (cyclin-dependent kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from 2-(6-methoxy-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-[4-(piperazin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

Phenotype where environments contain 2-(6-methoxy-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-[4-(piperazin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

Phenotype modified by environments containing 2-(6-methoxy-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-[4-(piperazin-1-yl)pyridin-3-yl]-1,3-thiazole-4-carboxamide

Human Disease / Model Data

Citations