rottlerin

Term ID

CHEBI:8899

Synonyms

• (2E)-1-[6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl]-3-phenylprop-2-en-1-one
• 3'-((8-cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl)-2',4',6'-trihydroxy-5'-methyl-acetophenone
• Kamalin
• Mallotoxin

Definition

A chromenol that is 2,2-dimethyl-2H-chromene substituted by hydroxy groups at positions 5 and 7, a 3-acetyl-2,4,6-trihydroxy-5-methylbenzyl group at position 6 and a (1E)-3-oxo-1-phenylprop-1-en-3-yl group at position 8. A potassium channel opener, it is isolated from Mallotus philippensis.

References

• CAS:82-08-6
• KEGG:C10721
• KNApSAcK:C00002708
• LIPID_MAPS_instance:LMPK12120428
• PMID:21415309
• PMID:22272173
• PMID:22410117
• PMID:22490701
• PMID:22758638
• PMID:22970301
• PMID:23632085
• Patent:EP2578210
• Patent:US2011112182
• Reaxys:70757
• Wikipedia:Rottlerin

Ontology

ChEBI  ( EBI )

Resources

CTD