trabectedin

Term ID

CHEBI:84050

Synonyms

• (6R,6aR,7R,13S,14S,16R,20R)-6',8,14-trihydroxy-7',9-dimethoxy-4,10,23-trimethyl-19-oxo-3',4',6,7,12,13,14,16-octahydro-2'H,6aH-spiro[7,13-epimino-6,16-(epithiopropanooxymethano)[1,3]dioxolo[7,8]isoquinolino[3,2-b][3]benzazocine-20,1'-isoquinolin]-5-yl ace
• Ect 743
• Ecteinascidin
• Ecteinascidin 743
• ET-743
• ET743
• trabectedin
• Yondelis

Definition

A tetrahydroisoquinoline alkaloid obtained from a Caribbean tunicate Ecteinascidia turbinata. Used for the treatment of soft tissue sarcoma and relapsed ovarian cancer.

References

• CAS:114899-77-3
• DrugBank:DB05109
• Drug_Central:4633
• HMDB:HMDB0015609
• KEGG:C16875
• KEGG:D06199
• PMID:18728699
• PMID:21403840
• PMID:21499557
• PMID:23149213
• PMID:24001124
• PMID:24277455
• PMID:24662672
• PMID:24692579
• PMID:24696229
• PMID:24707261
• PMID:24755886
• PMID:24756367
• PMID:24803896
• PMID:24844217
• PMID:24917554
• PMID:24941346
• PMID:24982387
• PMID:25048043
• PMID:25048044
• PMID:25050069
• PMID:25076252
• PMID:25100135
• PMID:25209722
• PMID:25263179
• PMID:25273374
• PMID:25479910
• Reaxys:7617615
• Wikipedia:Trabectedin

Ontology

ChEBI  ( EBI )

Resources

CTD