ent-diltiazem

Term ID

CHEBI:82813

Synonyms

(-)-cis-diltiazem
(2R,3R)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate
L-cis-diltiazem

Definition

A 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate in which both stereocentres have R configuration. It is a cGMP-activated K+ channel blocker.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate

5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate Show first 5 Terms
has_role: potassium channel blocker

potassium channel blocker Show first 5 Terms
inverse is_conjugate_acid_of: ent-diltiazem(1+)

ent-diltiazem(1+) Show first 5 Terms
inverse is_enantiomer_of: diltiazem

diltiazem Show first 5 Terms
is_conjugate_base_of: ent-diltiazem(1+)

ent-diltiazem(1+) Show first 5 Terms
is_enantiomer_of: diltiazem

diltiazem Show first 5 Terms

Phenotype

Phenotype resulting from ent-diltiazem

Phenotype where environments contain ent-diltiazem

Phenotype modified by environments containing ent-diltiazem

Human Disease / Model Data

Citations