Search Ontology:
ChEBI
vorapaxar
- Term ID
- CHEBI:82702
- Synonyms
-
- ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamate
- vorapaxar
- Definition
- A carbamate ester that is the ethyl ester of [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethynyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamic acid. A protease-activated receptor-1 antagonist used (as its sulfate salt) for the reduction of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease. It has been shown to reduce the rate of a combined endpoint of cardiovascular death, MI, stroke and urgent coronary revascularisation.
- References
-
- CAS:618385-01-6
- Drug_Central:4870
- KEGG:D09765
- PDBeChem:VPX
- PMID:23396280
- PMID:23426761
- PMID:23501976
- PMID:23530022
- PMID:24211500
- PMID:24402559
- PMID:24444781
- PMID:24627331
- PMID:24676931
- PMID:24729713
- PMID:24750101
- PMID:24962425
- PMID:25012288
- PMID:25129064
- PMID:25138682
- PMID:25262270
- Reaxys:12646121
- Wikipedia:Vorapaxar
- Ontology
- ChEBI ( EBI )
- is a type of
-
- has_role
-
- inverse is_conjugate_acid_of
-
- is_conjugate_base_of
-
Phenotype
Phenotype resulting from vorapaxar
Phenotype where environments contain vorapaxar
Phenotype modified by environments containing vorapaxar
Human Disease / Model Data
Citations