rac-nortilidine

Term ID

CHEBI:77829

Synonyms

(+-)-ethyl trans-2-methylamino-1-phenyl-3-cyclohexene-trans-1-carboxylate
nortilidine
rac-ethyl (1R,2S)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate
rac-ethyl (1S,2R)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate

Definition

A racemate comprising (1R,2S)- and (1S,2R)-nortilidine. The synthetic narcotic analgesic tilidine is a prodrug for nortilidine, being metabolised to it in the liver. Virtually all of the opioid analgesic effects of racemic nortilidine, which are comparable to those of morphine, are due to the (1S,2R) enantiomer.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: racemate

racemate Show first 5 Terms
has_part: (1R,2S)-nortilidine (1S,2R)-nortilidine

(1R,2S)-nortilidine (1S,2R)-nortilidine Show first 5 Terms
has_role: drug metabolite opioid analgesic

drug metabolite opioid analgesic Show first 5 Terms

Phenotype

Phenotype resulting from rac-nortilidine

Phenotype where environments contain rac-nortilidine

Phenotype modified by environments containing rac-nortilidine

Human Disease / Model Data

Citations