(+-)-menthol

Term ID

CHEBI:76310

Synonyms

(+/-)-menthol
d,l-menthol
dl-menthol
rac-(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol
rac-menthol
racementhol
racementholum
racementol

Definition

A racemate comprising equimolar amounts of (+)- and (-)-menthol. Both (+-)- and (-)-menthol are used to relieve symptoms of conditions such as bronchitis and sinusitis. When applied to the skin, menthol dilates the blood vessels, giving a sensation of coldness followed by an analgesic effect that relieves itching. It is therefore used in creams and ointments for the relief of pruritis and urticaria.

References

AGR:IND20570977
CAS:89-78-1
KEGG:D04849
PMID:12806393
PMID:18640200

Ontology

ChEBI ( EBI )

Relationships

is a type of: racemate

racemate Show first 5 Terms
has_part: (+)-menthol (-)-menthol

(+)-menthol (-)-menthol Show first 5 Terms
has_role: antipruritic drug antispasmodic drug antitussive vasodilator agent

antipruritic drug antispasmodic drug antitussive vasodilator agent Show first 5 Terms

Phenotype

Phenotype resulting from (+-)-menthol

Phenotype where environments contain (+-)-menthol

Phenotype modified by environments containing (+-)-menthol

Human Disease / Model Data

Citations