tyrphostin AG 825

Term ID

CHEBI:75405

Synonyms

(2E)-3-{3-[(1,3-benzothiazol-2-ylsulfanyl)methyl]-4-hydroxy-5-methoxyphenyl}-2-cyanoprop-2-enamide

Definition

An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth factor receptor antagonist.

References

PMID:20049896
PMID:9735325
Reaxys:14612999

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic ether benzothiazoles enamide nitrile organic sulfide ... Show All 7 Terms

aromatic ether benzothiazoles enamide nitrile organic sulfide phenols primary carboxamide Show first 5 Terms
has_functional_parent: 1,3-benzothiazole-2-thiol

1,3-benzothiazole-2-thiol Show first 5 Terms
has_role: epidermal growth factor receptor antagonist

epidermal growth factor receptor antagonist Show first 5 Terms

Phenotype

Phenotype resulting from tyrphostin AG 825

Phenotype where environments contain tyrphostin AG 825

Phenotype modified by environments containing tyrphostin AG 825

Human Disease / Model Data

Citations