lomitapide mesylate

Term ID

CHEBI:72299

Synonyms

1-(4-{9-[(2,2,2-trifluoroethyl)carbamoyl]-9H-fluoren-9-yl}butyl)-4-({[4'-(trifluoromethyl)biphenyl-2-yl]carbonyl}amino)piperidinium methanesulfonate
AEGR-733
BMS-201038
BMS-201038-04
Juxtapid
lomitapide methanesulfonate
lomitapide monomesylate
N-(2,2,2-trifluoroethyl)-9-{4-[4-({[4'-(trifluoromethyl)biphenyl-2-yl]carbonyl}amino)piperidin-1-yl]butyl}-9H-fluorene-9-carboxamide methanesulfonate

Definition

A methanesulfonate (mesylate) salt prepared from equimolar amounts of lomitapide and methanesulfonic acid. Used as a complement to a low-fat diet and other lipid-lowering treatments in patients with homozygous familial hypercholesterolemia.

References

CAS:202914-84-9
KEGG:D09638
PMID:12445582
PMID:17215532
PMID:21401695
Patent:WO2005087234
Patent:WO2007047722
Reaxys:14506420

Ontology

ChEBI ( EBI )

Relationships

is a type of: methanesulfonate salt

methanesulfonate salt Show first 5 Terms
has_part: lomitapide(1+)

lomitapide(1+) Show first 5 Terms
has_role: anticholesteremic drug MTP inhibitor

anticholesteremic drug MTP inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from lomitapide mesylate

Phenotype where environments contain lomitapide mesylate

Phenotype modified by environments containing lomitapide mesylate

Human Disease / Model Data

Citations