fluvirucin A1

Term ID

CHEBI:71508

Synonyms

(2R,3S,6R,10S)-3-[(3-amino-3,6-dideoxy-alpha-L-talopyranosyl)-oxy]-2,6-dimethyl-10-ethyl-13-tridecanelactam
(3R,4S,7R,11S)-11-ethyl-3,7-dimethyl-2-oxoazacyclotetradecan-4-yl 3-amino-3,6-dideoxy-alpha-L-talopyranoside

Definition

A lactam that is 4-hydroxyazacyclotetradecan-2-one substituted by an ethyl group at position 11, methyl groups at position 3 and 7 and a 3-amino-3,6-dideoxy-alpha-L-talopyranosyl moiety at position 4 via a glycosyl linkage (the 3R,4S,7R,11S stereoisomer). It is isolated from the fermentation broth of an unidentified actinomycete species and exhibits potent inhibitory activity against influenza A virus.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aminoglycoside lactam macrocycle

aminoglycoside lactam macrocycle Show first 5 Terms
has_role: antimicrobial agent EC 3.2.1.18 (exo-alpha-sialidase) inhibitor metabolite

antimicrobial agent EC 3.2.1.18 (exo-alpha-sialidase) inhibitor metabolite Show first 5 Terms
inverse has_functional_parent: 6-desmethyl-N-methylfluvirucin A1 N-methylfluvirucin A1

6-desmethyl-N-methylfluvirucin A1 N-methylfluvirucin A1 Show first 5 Terms

Phenotype

Phenotype resulting from fluvirucin A1

Phenotype where environments contain fluvirucin A1

Phenotype modified by environments containing fluvirucin A1

Human Disease / Model Data

Citations