tofacitinib citrate

Term ID

CHEBI:71197

Synonyms

3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate
CP-690,550-10
Tasocitinib citrate
Xeljanz

Definition

A citrate salt obtained by combining equimolar amounts of tofacitinib and citric acid. Used to treat moderately to severely active Rheumatoid Arthritis.

References

CAS:540737-29-9
KEGG:D09783
PMID:21105711
Patent:US2003130292
Patent:WO2005063251
Patent:WO2005105146
Reaxys:11610699

Ontology

ChEBI ( EBI )

Relationships

is a type of: citrate salt

citrate salt Show first 5 Terms
has_part: tofacitinib

tofacitinib Show first 5 Terms
has_role: antirheumatic drug EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor

antirheumatic drug EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from tofacitinib citrate

Phenotype where environments contain tofacitinib citrate

Phenotype modified by environments containing tofacitinib citrate

Human Disease / Model Data

Citations