orbiculin D

Term ID

CHEBI:66825

Synonyms

(3R,5S,5aS,6S,9R,9aS,10R)-6-(acetyloxy)-2,2,5a,9-tetramethyloctahydro-2H-3,9a-methano-1-benzoxepine-5,10-diyl difuran-3-carboxylate
1beta-acetoxy-6alpha,9alpha-di(3-furoyloxy)-dihydro-beta-agarofuran

Definition

A dihydroagarofuran sesquiterpenoid that consists of dihydro-beta-agarofuran substituted by acetoxy group at position 1 and furoyloxy groups at positions 6 and 9 (the 1beta,6alpha,9alpha stereoisomer). Isolated from Celastrus orbiculatus, it exhibits inhibition of both NF-kappaB activation and nitric oxide production.

References

PMID:10346948
Reaxys:8366521

Ontology

ChEBI ( EBI )

Relationships

is a type of: acetate ester bridged compound cyclic ether dihydroagarofuran sesquiterpenoid organic heterotricyclic compound

acetate ester bridged compound cyclic ether dihydroagarofuran sesquiterpenoid organic heterotricyclic compound Show first 5 Terms
has_functional_parent: 3-furoic acid

3-furoic acid Show first 5 Terms
has_role: metabolite NF-kappaB inhibitor

metabolite NF-kappaB inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from orbiculin D

Phenotype where environments contain orbiculin D

Phenotype modified by environments containing orbiculin D

Human Disease / Model Data

Citations